MyBioSource.com's PHC2 Rabbit pAb is a Rabbit Polyclonal antibody. This antibody has been shown to work in applications such as: Western Blot. The PHC2 Rabbit pAb Antibody was generated using PHC2 as the antigen and it reacts with Human.
Description
Component of a Polycomb group (PcG) multiprotein PRC1-like complex, a complex class required to maintain the transcriptionally repressive state of many genes, including Hox genes, throughout development. PcG PRC1 complex acts via chromatin remodeling and modification of histones; it mediates monoubiquitination of histone H2A 'Lys-119', rendering chromatin heritably changed in its expressibility. The hPRC-H complex purification reported by PubMed:12167701 probably presents a mixture of different PRC1-like complexes